Gac is a transcriptional repressor of the Lyme disease spirochete's OspC virulence-associated surface protein
T. N. Castro-Padovani, T. C. Saylor, O. T. Husted, A. C. Krusenstjerna, N. Jusufovic, B. Stevenson
This paper identifies Gac as a transcriptional repressor of the OspC virulence protein in Lyme disease spirochetes, showing its role in regulating OspC expression during infection.
bioRxiv · Nov 9, 2022 · PreprintMicrobiology