Further Exploration of the SAR of Imidazoquinolines; Identification of Potent C7 Substituted Imidazoquinolines
J. Hunt, P. A. Kleindl, R. Moulder, T. E. Prisinzano, M. L. Forrest
This study explores the structure-activity relationship of C7-substituted imidazoquinolines, identifying compounds with increased potency and altered cytokine profiles compared to existing TLR7/8 agonists.
bioRxiv · Oct 4, 2019 · PreprintBioengineering