Notch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesis.
M. Mukherjee, I. Ratnayake, M. Janga, E. Fogarty, S. Scheidt, J. deRiso, J. Grassmeyer, I. Chandrasekar, P. Ahrenkiel, R. Kopan, K. Surendran
The paper shows that Notch signaling regulates Akap12 expression and primary cilia length, affecting renal tubule morphogenesis and linking Notch defects to ciliopathies.
bioRxiv · Sep 9, 2019Cell Biology