Increased Relative Biological Effectiveness of Orthovoltage X-rays Compared to γ-rays in Preclinical Irradiation
B. I. Bell, J. Vercellino, N. P. Brodin, C. Velten, L. S. Y. Nanduri, K. E. Tanaka, Y. Fang, Y. Wang, R. Macedo, J. English, M. M. Schumacher, P. K. Duddempudi, P. Asp, W. Koba, S. Shajahan, , C. Guha
This study compares the biological effects of orthovoltage X-rays and 137Cs γ-rays in mouse models, finding that lower-energy X-rays cause more severe hematopoietic and intestinal injury at equivalent physical doses.
bioRxiv · Feb 18, 2022Pathology