Author

P. D. Carr

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

C. Jackson· 1 shared D. W. Anderson· 1 shared E. Bornberg-Bauer· 1 shared E. Dohmen· 1 shared F. Baier· 1 shared G. Yang· 1 shared N. Hong· 1 shared N. Tokuriki· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

C. Jackson

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1 paper

Recent·Most cited

Higher-order epistatic networks underlie the evolutionary fitness landscape of a xenobiotic- degrading enzyme

G. Yang, D. W. Anderson, F. Baier, E. Dohmen, N. Hong, P. D. Carr, S. C. L. Kamerlin, C. Jackson, E. Bornberg-Bauer, N. Tokuriki

This study identifies five mutations that enable the evolution of a xenobiotic-degrading enzyme and shows that higher-order epistasis shapes its adaptive landscape and substrate specificity.

bioRxiv · Dec 26, 2018 · PreprintBiochemistry