Natural and engineered isoforms of the inflammasome adaptor ASC form non-covalent, pH-responsive hydrogels
E. A. Gaspar-Morales, A. Waterston, P. Diaz-Parga, A. M. Smith, M. Sadqi, A. Gopinath, R. C. Andresen Eguiluz, E. de Alba
The paper demonstrates that natural and engineered ASC isoforms form non-covalent, pH-responsive hydrogels through self-assembly, revealing their potential for bioinspired material design.
bioRxiv · May 3, 2023Bioengineering