Cholesterol Oxidation Modulates the Formation of Liquid-Ordered Domains in Model Membranes
P. Smith, P. G. Petrov, C. D. Lorenz
This paper shows that 7-ketocholesterol disrupts liquid-liquid phase separation in model membranes through two mechanisms, providing a molecular explanation for its role in apoptosis.
bioRxiv · May 24, 2021 · PreprintBiophysics