A Mechanistic Model for the Release of Ceramide from the CERT START Domain
M. Moqadam, P. Gartan, R. Talandashti, A. Chiapparino, K. Titeca, A.-C. Gavin, N. Reuter
The paper proposes a membrane-assisted mechanism for ceramide release from the CERT START domain using molecular simulations and validates it with experimental lipidomics data.
bioRxiv · Dec 16, 2023Biophysics