Author

P. Hopcroft

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Cell Biology· 1

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Approach:Bayesian inference· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Hock· 1 shared A. M. Afzal· 1 shared B. Zhang· 1 shared E. Semenova· 1 shared G. Kadamur· 1 shared M. L. Guerriero· 1 shared S. E. Lazic· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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1 shared paperCell Biology

A. Hock

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1 paper

Recent·Most cited

Flexible fitting of PROTAC concentration-response curves with changepoint Gaussian Processes

E. Semenova, M. L. Guerriero, B. Zhang, A. Hock, P. Hopcroft, G. Kadamur, A. M. Afzal, S. E. Lazic

This paper introduces a Bayesian changepoint Gaussian Processes model to automatically fit PROTAC concentration-response curves, enabling accurate parameter estimation and compound ranking without manual intervention.

bioRxiv · Nov 13, 2020Cell Biology