Low force unfolding of a single-domain protein by parallel pathways
P. I. Zhuravlev, M. Hinczewski, D. Thirumalai
The paper shows that upward curvature in log ku(f) as a function of force indicates parallel unfolding pathways in single-domain proteins, supported by simulations of β-sandwich proteins and mutants.
bioRxiv · Dec 19, 2020Biophysics