Single-molecule measurements reveal that PARP1 condenses DNA by loop formation
N. A. W. Bell, P. J. Haynes, K. Brunner, T. Maia de Oliveira, M. Flocco, B. W. Hoogenboom, J. E. Molloy
This study shows PARP1 condenses undamaged DNA through loop formation using single-molecule techniques, revealing a mechanism for chromatin organization.
bioRxiv · Sep 15, 2020Biophysics