Extending the application of the SCA/Sectors method for the identification of domain boundaries and subtype specific residues in multi-domain biosynthetic proteins: Application to Polyketide Synthases
T. Oruc, C. M. Thomas, P. J. Winn
This paper extends the SCA/Sectors method to identify domain boundaries and subtype-specific residues in polyketide synthases, showing co-evolving residue networks correlate with domain functions and boundaries.
bioRxiv · Jun 30, 2021 · PreprintBioengineering