Author

C. M. Thomas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

T. C. McLean· 2 shared B. T. Chait· 1 shared C. A. Elg· 1 shared C. Aicart-Ramos· 1 shared D. ANDRIVON· 1 shared D. M. Lawson· 1 shared E. A. Campbell· 1 shared E. M. Top· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

T. C. McLean

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing

T. C. McLean, F. Balaguer-Perez, J. Chandanani, C. M. Thomas, C. Aicart-Ramos, S. Burick, P. D. B. Olinares, G. Gobbato, J. E. A. Mundy, B. T. Chait, D. M. Lawson, S. A. Darst, E. A. Campbell, F. Moreno-Herrero, T. B. K. Le

The paper shows that KorB, a DNA-sliding clamp, switches to a repressor role with KorA to mediate long-range gene silencing on plasmid RK2.

bioRxiv · Feb 16, 2024 · PreprintMicrobiology

Evolution of a Plasmid Regulatory Circuit Ameliorates Plasmid Fitness Cost

C. A. Elg, E. Mack, M. Rolfsmeier, T. C. McLean, O. Kosterlitz, E. Soderling, S. Narum, P. A. Rowley, C. M. Thomas, E. M. Top

This study shows that inactivating the upf31 gene in a plasmid improves its maintenance in E. coli by altering gene regulation, demonstrating how plasmid evolution can affect host range.

bioRxiv · Feb 5, 2024Microbiology

Extending the application of the SCA/Sectors method for the identification of domain boundaries and subtype specific residues in multi-domain biosynthetic proteins: Application to Polyketide Synthases

T. Oruc, C. M. Thomas, P. J. Winn

This paper extends the SCA/Sectors method to identify domain boundaries and subtype-specific residues in polyketide synthases, showing co-evolving residue networks correlate with domain functions and boundaries.

bioRxiv · Jun 30, 2021 · PreprintBioengineering

The Drosophila EGFR ligand mSpitz is delivered to cytoplasmic capes at sites of non-canonical RNA export on the nuclear envelope via the endosomal system

F. J. Mattie, P. Kumar, M. D. Travor, K. C. Browder, C. M. Thomas

bioRxiv · Jul 14, 2020 · PreprintCell Biology

Potato genotypes differentially alter the expression of Phytophthora infestans effectors during PAMP-mediated resistance induction

C. M. THOMAS, P. LE BOULCH, D. ANDRIVON, F. VAL

The paper examines how different potato genotypes affect the expression of Phytophthora infestans effectors during PAMP-mediated resistance, finding genotype-dependent changes in effector and defense gene expression and disease severity.

bioRxiv · Feb 14, 2019 · PreprintPlant Biology