Author

P. N. Dyer

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Biophysics· 1

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Approach:experimental assay· 1

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J. Mahadevan· 1 shared J. Rudolph· 1 shared K. Luger· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBiophysics

J. Mahadevan

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1 paper

Recent·Most cited

Poly(ADP-ribose) polymerase 1 Searches DNA via a ‘Monkey Bar’ Mechanism

J. Rudolph, J. Mahadevan, P. N. Dyer, K. Luger

This study reveals that PARP1 searches DNA using a 'monkey bar' mechanism, where DNA binding facilitates release, and identifies the WGR-domain as essential for this process.

bioRxiv · May 18, 2018Biophysics