Author

P. P. Tak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:statistical model· 1

Frequent Co-Authors

D. M. Gerlag· 2 shared B. van Kuijk· 1 shared D. C. Anang· 1 shared I. Y. Choi· 1 shared J. F. Semmelink· 1 shared J. Hahnlein· 1 shared K. P. van Lienden· 1 shared L. G. M. van Baarsen· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

D. M. Gerlag

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2 papers

Recent·Most cited

Increased frequency of CD4+ and CD8+ follicular helper T cells in human lymph node biopsies during the earliest stages of rheumatoid arthritis

D. C. Anang, T. H. Ramwadhdoebe, J. Hahnlein, B. van Kuijk, N. Smits, K. P. van Lienden, M. Maas, D. M. Gerlag, P. P. Tak, N. de Vries, L. G. van Baarsen

The paper examines Tfh cell frequencies and cytokine profiles in lymph node biopsies of early RA patients and RA-risk individuals, finding increased Tfh cells correlating with B cell numbers and reduced IL-21 production.

bioRxiv · Nov 10, 2021Immunology

Synovial Gene Signatures Associated with the Development of Rheumatoid Arthritis in At Risk Individuals: a Prospective Study

L. G. M. van Baarsen, T. A. de Jong, M. J. H. de Hair, J. F. Semmelink, I. Y. Choi, D. M. Gerlag, P. P. Tak

This study identifies gene expression signatures in synovial tissue of at-risk individuals that predict the development of rheumatoid arthritis before clinical onset.

bioRxiv · Apr 27, 2021 · PreprintImmunology