Mutation accumulation differentially impacts ageing in mammalian tissues
Z. G. Turan, P. Parvizi, H. M. Donertas, J. Tung, P. Khaitovich, M. Somel
The paper tests the mutation accumulation hypothesis by analyzing gene expression and conservation across tissues, finding age-related decreases in transcriptome conservation in some tissues but not others.
bioRxiv · Jan 15, 2018Evolutionary Biology