M. Somel

Population genomic history of the endangered Anatolian and Cyprian mouflons in relation to worldwide wild, feral and domestic sheep lineages

This study analyzes the population history and genetic diversity of Anatolian and Cyprian mouflons compared to other sheep lineages, finding genetic affinity with domestic sheep and disparities in diversity and mutation load.

Investigating DNA methylation changes associated with food production using paleogenomes

The paper investigates DNA methylation changes in ancient genomes to assess epigenetic impacts of the Neolithic transition but finds no systematic methylation differences related to diet or lifestyle.

Ancient Sheep Genomes reveal four Millennia of North European Short-Tailed Sheep in the Baltic Sea region

This study analyzes ancient sheep genomes from the Baltic Sea region to show long-term continuity of short-tailed breeds and loss of genetic diversity in modern times.

Under the shadow: Old-biased genes are subject to weak purifying selection at both the tissue and cell type-specific levels

The paper shows that old-biased genes show weaker purifying selection in multiple tissues and cell types across diverse species, supporting the mutation accumulation theory of aging.

Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication

This study analyzes ancient sheep DNA from Anatolia to reveal a complex demographic history, including a domestication bottleneck and later admixture from other regions.

Mutation accumulation differentially impacts ageing in mammalian tissues

The paper tests the mutation accumulation hypothesis by analyzing gene expression and conservation across tissues, finding age-related decreases in transcriptome conservation in some tissues but not others.

Archaeogenetics of Late Iron Age Cemialo Sırtı, Batman: Investigating maternal genetic continuity in North Mesopotamia since the Neolithic

The paper analyzes mitochondrial DNA from Late Iron Age remains in North Mesopotamia to assess maternal genetic continuity from the Neolithic to the present.