Immunosuppressive traits of the hybrid epithelial/mesenchymal phenotype
S. Sahoo, S. P. Nayak, K. Hari, P. Purkait, S. Mandal, A. Kishore, H. Levine, M. K. Jolly
The paper investigates immune-evasive strategies of hybrid epithelial/mesenchymal (E/M) cells using a regulatory network model and RNA-seq data, showing they can exhibit high PD-L1 levels without full EMT.
bioRxiv · Jun 21, 2021Cancer Biology