1H NMR chemical exchange techniques reveal local and global effects of oxidized cytosine derivatives
R. C. A. Dubini, E. Korytiakova, T. Schinkel, P. Heinrichs, T. Carell, P. Rovo
This study uses NMR to show that 5caC destabilizes DNA globally and increases base-pair mobility locally, with effects dependent on pH and temperature.
bioRxiv · Dec 14, 2021Biophysics