Did variants in inborn errors of immunity genes contribute to the extinction of Neanderthals?
Z. Zhou, S. M. A. Swagemakers, M. S. Lourens, N. Suratannon, P. van der Spek, V. A. S. H. Dalm, W. A. Dik, H. IJspeert, P. M. van Hagen
The paper investigates whether harmful immune-related genetic variants from Neanderthals contributed to their extinction by analyzing variants in inborn errors of immunity genes across Neanderthal and Denisovan genomes.
bioRxiv · Oct 19, 2022 · PreprintEvolutionary Biology