Single-nucleotide Differences and Cell Type Decide the Subcellular Localization of miRNA Isoforms (isomiRs), tRNA-derived Fragments (tRFs) and rRNA-derived Fragments (rRFs)
Tess Cherlin, Jing Yi, Venetia Pliatsika, Haley Wilson, Lily Thompson, Panagiotis I. Vlantis, Phillipe Loher, Benjamin E. Leiby, Isidore Rigoutsos
The paper investigates the subcellular localization of miRNA isoforms, tRFs, and rRFs across three cell lines, revealing that their localization depends on sequence and cell type, and creates an atlas of their distribution.
bioRxiv · Aug 22, 2022 · PreprintMolecular Biology