Low-dose doxorubicin drives caveolin-1 depended re-epithelialization of breast cancer cells as a mechanism of cancer plasticity
Alexandros F. Damalas, Marijonas Tutkus, Ioannis D. Kyriazis, Zozo Outskouni, Ernesta Vitulskienė, Panteleimon Dimovelis M Dimovelis, Soultana Kafetzi, Charalampos E. Angelidis, Panagiotis Liakos, Varvara Trachana
This study shows low-dose doxorubicin induces caveolin-1-dependent re-epithelialization in breast cancer cells, altering membrane organization, epithelial phenotype, and autophagy.
bioRxiv · Sep 29, 2026 · PreprintCancer Biology