Impaired ureagenesis due to arginine-insensitive N-acetylglutamate synthase
Parthasarathy Sonaimuthu, Emilee Senkevitch, Nantaporn Haskins, Prech Uapinyoying, Markey McNutt, Hiroki Morizono, Mendel Tuchman, Ljubica Caldovic
The paper investigates the role of L-arginine in NAGS activation and ureagenesis by studying NAGS knockout mice and a human patient with a related mutation.
bioRxiv · Sep 25, 2018 · PreprintMolecular Biology