SAMP-Score: A morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells
Ryan Wallis, Bethany K. Hughes, Madeleine Moore, Emily A. O’Sullivan, Luke C. McIlvenna, Luke Gammon, Anthony G. Hope, Fiona Bellany, Parul Dixit, Claire J. Mackenzie, Charlotte Green, David W. Gray, Cleo L. Bishop
SAMP-Score identifies pro-senescence compounds in Sen-Mark+ cancers by classifying senescence based on morphology, leading to the discovery of QM5928.
Aging · Oct 30, 2025Peer-reviewedCancer Biology