Sensory Neuropeptides Dictate Sex-Specific Synovial Immunity and Cartilage Degeneration in Aging Mice
Patrick Pann, Ravikumar Mayakrishnan, Babak Moradi, Brian Johnstone, Susanne Grässel
This study shows that neuropeptides SP and CGRP influence sex-specific synovial immunity and cartilage degradation in aging mice, with their absence providing structural protection.
bioRxiv · Jul 27, 2026 · PreprintPathology