Characterization of the African Swine Fever Virus transcriptome and the associated innate immune response reveals key features of virulence
Aurélien Leroy, Juliette Dupré, Pauline Barbarin, Théo Ferré, Janette Godard, Chloé Styranec, Vanaïque Guillory, Isabelle Fleurot, Marie-Frédérique Le Potier, Olivier Bourry, Julien Pichon, Sascha Trapp, Grégory Caignard, Ignacio Caballero, Ferdinand Roesch
This study compares virulent and attenuated ASFV strains to identify differences in viral gene expression and host immune response that contribute to virulence.
bioRxiv · Oct 31, 2025 · PreprintMicrobiology