Molecular dynamics simulation study reveals effects of key mutations on spike protein structure in SARS-CoV-2
Jerome Rumdon Lon, Binbin Xi, Bingxu Zhong, Yiyuan Zheng, Zixi Chen, Ruoran Qiu, Siqing Zhang, Pei Guo, Hongli Du
This study uses molecular dynamics simulations to analyze how key mutations in SARS-CoV-2 spike protein affect its structure and stability, finding that some mutations enhance stability while others increase solvent accessibility.
bioRxiv · Feb 3, 2021 · PreprintBioinformatics