Binbin Xi

PepCleav evaluates peptide cleavability by classifying amino acids at proteasome and aminopeptidase sites, improving neoantigen identification with 84-89% cleavable peptide accuracy.

This study uses molecular dynamics simulations to analyze how key mutations in SARS-CoV-2 spike protein affect its structure and stability, finding that some mutations enhance stability while others increase solvent accessibility.

AutoVEM2 is a flexible automated tool for analyzing candidate key mutations and epidemic trends in viruses, demonstrating its effectiveness with SARS-CoV-2, HBV, and HPV-16.

The paper introduces an automated tool, AutoVEM, to monitor SARS-CoV-2 haplotype subgroup trends and key mutations, analyzing 131,576 genomes in 18 hours.