Author

Pengpeng Wu

Tongji University

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:multiome· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

Caibin Zhou· 1 shared Chenfei WangiD· 1 shared Hailin Wei· 1 shared Xihao Sherlock HuiD· 1 shared Xinwei Zheng· 1 shared Yazi LiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Caibin Zhou

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1 paper

Recent·Most cited

Decoding Single-Cell Omics of Perturbation Responses Using DeSCOPE

Pengpeng Wu, Hailin Wei, Yazi Li, Xinwei Zheng, Caibin Zhou, Xihao Sherlock Hu, Chenfei Wang

DeSCOPE is a variational autoencoder framework for predicting genetic perturbation responses across multiple omics modalities, outperforming baselines in unseen gene and cell type scenarios.

bioRxiv · Apr 15, 2026 · PreprintBioinformatics