Optimised in-solution enrichment of over a million ancient human SNPs
Roberta Davidson, Xavier Roca‐Rada, Shyamsundar Ravishankar, Leonard Taufik, Christian Haarkötter, Evelyn Collen, Matthew P. Williams, Peter Webb, M. Irfan Mahmud, Erlin Novita Idje Djami, Gludhug A. Purnomo, Cristina Maria Pereira dos Santos, Assumpció Malgosa Morera, Linda Manzanilla, Ana María Silva, , Bastien Llamas
This study evaluates the effectiveness of the Twist Ancient DNA reagent for enriching ancient human SNPs, finding it robust for up to 27% endogenous DNA content with two rounds of enrichment.
bioRxiv · May 16, 2024 · PreprintGenomics