Author

Phillip S.C. Yam

Chinese University of Hong Kong

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

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Jinghan HuangiD· 1 shared Nelson L.S. TangiD· 1 shared

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2025-2025 · peak 1/yr

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Jinghan HuangORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 7, 2025

'Trans-differentiation of neutrophils from plasmablast' is an artefact caused by over-reliance on machine algorithms in single cell RNA sequencing analysis: Lesson learnt and steps ahead

Jinghan Huang, Phillip S.C. Yam, Nelson L.S. Tang

The paper shows that trans-differentiation of plasmablasts to neutrophils in scRNA-seq data is an artefact caused by low-quality cells and highlights the need for improved statistical standards and quality control in single-cell analysis.

2 citations

humanscRNA-seq

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