Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development.
Sung‐Eun Kim, Pooja J. Chothani, Rehana Shaik, Westley Pollard, Richard H. Finnell
This study shows that deleting Gpr161 in the Pax3 lineage in mice causes spinal and craniofacial defects due to altered Shh and Wnt signaling.
Disease Models & Mechanisms · Oct 27, 2023Peer-reviewedGenetics