A Counterfactual Framework for Directional Cell-Cell Interaction Analysis in Spatial Transcriptomics
Humaira Anzum, Veena Kochat, Md Ishtyaq Mahmud, Jagan Mohan Reddy Dwarampudi, Suresh Satpati, Pooja Shukla, Milind Javle, Lawrence Kwong, Kunal Rai, Tania Banerjee
This paper introduces a counterfactual framework to analyze directional cell-cell interactions in spatial transcriptomics, identifying significant asymmetric influences between tumor, immune, and stromal compartments in cholangiocarcinoma tissue.
Lecture notes in computer science · Sep 24, 2026Peer-reviewedCell Biology