Deciphering the Biosynthetic Potential of Microbial Genomes Using a BGC Language Processing Neural Network Model
Qilong Lai, Shuai Yao, Yuguo Zha, Haohong Zhang, Haobo Zhang, Ying Ye, Yonghui Zhang, Hong Wu Bai, Kang Ning
This paper introduces BGC-Prophet, a transformer-based model for identifying and extrapolating biosynthetic gene clusters (BGCs) in microbial genomes and metagenomes, revealing evolutionary patterns and enhancing BGC discovery.
Nucleic Acids Research · Apr 3, 2025Peer-reviewedBioinformatics