Yonghui Zhang

This paper develops a non-planar perylene diimide compound that targets both mitochondrial membrane potential and mtDNA transcription, showing antitumor effects in breast cancer models.

BGC-Finder uses protein language models to detect and annotate biosynthetic gene clusters in microbial genomes and metagenomes, improving speed and detection of core genes and cytochrome P450s.

This paper introduces BGC-Prophet, a transformer-based model for identifying and extrapolating biosynthetic gene clusters (BGCs) in microbial genomes and metagenomes, revealing evolutionary patterns and enhancing BGC discovery.