Genome-wide association study of adolescent-onset depression
Poppy Zenzi Grimes, Brittany L. Mitchell, Katherine Nina Thompson, Qingkun Deng, Xueyi Shen, Jareth C. Wolfe, Jodi T. Thomas, Robyn E. Wootton, Daniel E. Adkins, Saranya Arirangan, Elham Assary, Chris Chatzinakos, Charlotte A. Dennison, Swathi Hassan Gangaraju, Andreas Jangmo, , Alex S. F. Kwong
This study identifies 52 genetic variants associated with adolescent-onset depression through a large GWAS, revealing age-specific mechanisms and potential drug targets.
medRxiv · Sep 26, 2025 · PreprintGenetic & Genomic Medicine