Jareth C. Wolfe

This study identifies 52 genetic variants associated with adolescent-onset depression through a large GWAS, revealing age-specific mechanisms and potential drug targets.

This study conducts a genome-wide association study (GWAS) of ME/CFS, identifying eight genetic loci associated with the disease, suggesting involvement of immune and neurological processes.

Stator identifies cell types, subtypes, and states in single-cell data by analyzing higher-order gene expression dependencies, revealing cryptic states and subtypes not captured by proximity-based clustering.

This study shows that depletion of architectural proteins affects TAD organisation and gene expression in Drosophila, linking TAD reorganisation to changes in gene expression.