The assembly and efflux processes revealed by in situ structures of the ABC-type tripartite pump MacAB-TolC
Tong Huo, Wenfang Zhang, Zhili Yu, Wei Zheng, Yaoming Wu, Qiuyu Ren, Zekai Wan, Jun‐Li Cao, Zhao Wang, Xiaodong Shi
The paper resolves the in situ structures of the MacAB-TolC efflux pump in E. coli, revealing its assembly process and substrate-driven efflux mechanism.
Communications Biology · Jun 3, 2025Peer-reviewedMicrobiology