Genetic variation and RNA structure regulate microRNA biogenesis
N. Fernandez, R. A. Cordiner, R. S. Young, N. Hug, S. Macias, J. F. Caceres
The paper shows a genetic variant in pri-mir-30c-1 alters RNA structure, enhancing SRSF3 binding and increasing miR-30c levels in vitro and in cells.
Nature Communications · May 3, 2017Peer-reviewedBiochemistry