microRNAs (miR 9, 124, 155 and 224) transdifferentiate macrophages to neurons
This paper demonstrates that miR 9, 124, 155, and 224 can transdifferentiate macrophages into neurons without exogenous transcription factors, achieving 18-21% efficacy and inducing neuronal markers and functional activity.
bioRxiv · Jul 19, 2020Cell Biology