Cell Ecosystem and Signaling Pathways of Primary and Metastatic Pediatric Posterior Fossa Ependymoma
R. Aubin, E. C. Troisi, A. N. Alghalith, M. P. Nasrallah, M. Santi, P. G. Camara
This study identifies the cell ecosystem and signaling pathways of pediatric posterior fossa ependymoma using single-cell transcriptomics and shows WNT/β-catenin and TGF-β signaling drive tumorigenesis.
bioRxiv · Aug 10, 2020 · PreprintCancer Biology