Author

R. Barutcu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:rat· 2 Research Focus:benchmarking· 1 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

M. B. Black· 2 shared M. E. Andersen· 2 shared A. Y. Efremenko· 1 shared J. Harrill· 1 shared M. Black· 1 shared P. D. McMullen· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

M. B. Black

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Investigating the mode of action for wasting produced by tetrachlorodibenzo-p-dioxin (TCDD) in rats using transcriptomics: Evidence for roles of AHR and ARNT in circadian cycling

M. E. Andersen, R. Barutcu, M. B. Black, J. Harrill

This study investigates TCDD-induced wasting in rats using transcriptomics, showing AHR and ARNT involvement in circadian disruption and metabolic gene downregulation at high doses.

bioRxiv · Mar 2, 2024 · PreprintPharmacology & Toxicology

Investigating the mode of action for liver toxicity and wasting-like responses produced by high dose exposures to longer chain perfluoroacid substances (PFAS) using high throughput transcriptomics

R. Barutcu, M. Black, M. E. Andersen

This study identifies pathway perturbations in liver caused by PFAS exposure, showing longer-chain PFAS downregulate lipid and steroid metabolism genes, similar to TCDD, suggesting a common MOA involving PPAR inhibition.

bioRxiv · Mar 2, 2024 · PreprintPharmacology & Toxicology

Impact of gene selection criteria on transcriptomic ontology-based point of departure estimates

M. B. Black, A. Y. Efremenko, R. Barutcu, P. D. McMullen

The paper evaluates how gene selection criteria affect transcriptomic-based point of departure estimates in toxicology using rat kidney and liver data.

bioRxiv · Oct 20, 2023 · PreprintPharmacology & Toxicology