In vivo generation of post-infarct mouse cardiac muscle by cardiomyocyte progenitors produced with a reproducible laminin-promoted human stem cell differentiation system
L. Yap, J.-W. Wang, A. Moreno-Moral, L. Y. Chong, Y. Sun, N. Harmston, X. Wang, S. Y. Chong, M. K. Ohman, H. Wei, R. Bunte, S. Ghosh, S. Cook, O. Hovatta, D. P. V. de Kleijn, , K. Tryggvason
This paper develops a reproducible method to generate cardiac muscle progenitors from human stem cells using laminin-221, which can form human heart muscle in vivo after transplantation.
bioRxiv · Nov 26, 2018 · PreprintCell Biology