Author

K. Tryggvason

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

L. Y. Chong· 2 shared L. Yap· 2 shared A. Mansson· 1 shared A. Moreno-Moral· 1 shared A.-S. Johansson· 1 shared C. Tan· 1 shared D. P. V. de Kleijn· 1 shared E. G. Petretto· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

L. Y. Chong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Skin mesenchymal niches maintain and protect AML-initiating stem cells

L. Sandhow, H. Cai, E. Leonard, P. Xiao, L. Tomaipitinca, A. Mansson, M. Kondo, X. Sun, A.-S. Johansson, K. Tryggvason, M. Kasper, M. Jaras, H. QIAN

The paper shows skin mesenchymal niches protect AML-initiating stem cells from chemotherapy and promote chemoresistance in a mouse model.

bioRxiv · May 20, 2022Cancer Biology

PLURIPOTENT STEM CELL-DERIVED CARDIOVASCULAR PROGENITORS DIFFFERENTIATED ON LAMININ 221 REGENERATE AND IMPROVE FUNCTION OF INFARCTED SWINE HEARTS

L. Yap, L. Y. Chong, C. Tan, S. Adusumalli, M. Seow, J. Guo, Z. Cai, S. J. Loo, E. Lim, N. Lath, L. Ye, E. G. Petretto, K. Tryggvason

This paper differentiates pluripotent stem cells into cardiovascular progenitors on laminin 221 and shows improved heart function in infarcted pigs.

bioRxiv · Apr 29, 2021 · PreprintCell Biology

In vivo generation of post-infarct mouse cardiac muscle by cardiomyocyte progenitors produced with a reproducible laminin-promoted human stem cell differentiation system

L. Yap, J.-W. Wang, A. Moreno-Moral, L. Y. Chong, Y. Sun, N. Harmston, X. Wang, S. Y. Chong, M. K. Ohman, H. Wei, R. Bunte, S. Ghosh, S. Cook, O. Hovatta, D. P. V. de Kleijn, , K. Tryggvason

This paper develops a reproducible method to generate cardiac muscle progenitors from human stem cells using laminin-221, which can form human heart muscle in vivo after transplantation.

bioRxiv · Nov 26, 2018 · PreprintCell Biology