R. C. Penner

Protein Geometry, Function and Mutation

The paper explores how protein secondary structure influences mutation rates in viral glycoproteins, particularly the SARS-CoV-2 spike protein, by analyzing the role of backbone hydrogen bonds.

Mutagenic distinction between the receptor-binding and fusion subunits of the SARS-CoV-2 spike glycoprotein and its upshot

The paper identifies mutagenic differences between S1 and S2 subunits of SARS-CoV-2 spike glycoprotein and suggests Delta as an intermediary in Omicron evolution.