A disordered encounter complex is central to the yeast Abp1p SH3 domain binding pathway
G. J. Gerlach, R. Carrock, R. Stix, E. J. Stollar, K. A. Ball
This study uses molecular dynamics simulations to show that the SH3 domain binding pathway of the yeast Abp1p involves a flexible encounter complex stabilized by hydrophobic and electrostatic interactions.
PLOS Computational Biology · Sep 14, 2020Peer-reviewedBiophysics