AICAR prevents doxorubicin-induced heart failure in rats by ameliorating cardiac atrophy and improving fatty acid oxidation
A. Choksey, B. D. Thackray, V. Ball, L. Hong Tuan Ha, E. Sharma, B. W. Kennedy, R. D. Carter, J. Broxholme, M. P. Murphy, L. C. Heather, D. J. Tyler, K. N. Timm
This study shows AICAR prevents doxorubicin-induced heart failure in rats by improving cardiac function, mitochondrial fatty acid oxidation, and preventing myocardial atrophy.
bioRxiv · Aug 17, 2022 · PreprintBiochemistry