Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis
A. S. Joshi, M. B. Castillo, M. Tomaz da Silva, A. T. Vuong, P. H. Gunaratne, R. Darabi, Y. Liu, A. Kumar
This study shows that XBP1 in myofibers regulates muscle regeneration through cell-autonomous and non-autonomous mechanisms by affecting satellite cells and non-myogenic cells.
bioRxiv · Jun 3, 2024Cell Biology