Systematic Evaluation of High-Throughput PBK Modelling Strategies for the Prediction of Intravenous and Oral Pharmacokinetics in Humans
R. Geci, D. Gadaleta, M. Garcia de Lomana, R. Ortega-Vallbona, E. Colombo, E. Serrano-Candelas, A. Paini, L. Kuepfer, S. Schaller
This study evaluates high-throughput PBK modelling strategies for predicting human intravenous and oral pharmacokinetics using in vitro and in silico data.
bioRxiv · Mar 20, 2024Pharmacology & Toxicology