Extracellular matrix dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and response in fibroblasts.
W. Sturgess, S. Packirisamy, R. Geneidy, V. S. Swaminathan
This study shows Septin-7 is an FA protein regulated by ECM and integrin activation, which differentially regulates FA subpopulations to promote mechanosensing and ECM remodeling in fibroblasts.
bioRxiv · Feb 27, 2024 · PreprintCell Biology